Synthesis, characterization, antimicrobial studies, and molecular docking studies of transition metal complexes formed from a benzothiazole-based azo ligand
نویسندگان
چکیده
ABSTRACT. The azo ligand obtained from the diazotization reaction of 2-aminobenzothiazole and 4-nitroaniline yielded a novel series complexes with Co(II), Ni(II), Cu(II), Zn(II) ions. were investigated using spectral techniques such as UV-Vis, FT-IR, 1H 13C NMR spectroscopic analyses, LC-MS atomic absorption spectrometry, electrical conductivity, magnetic susceptibility. molar ratio synthesized compounds was determined exchange ratio, which revealed metal-ligand ratios in isolated 1:2. tested for antimicrobial activity against S. aureus, E. coli, C. albicans, tropicalis bacterial species. Additionally, their binding affinities predicted molecular docking analysis, pharmacokinetic drug-likeness properties evaluated.
 
 KEY WORDS: Azo ligand, Metal complexes, Antimicrobial studies, Molecular study
 Bull. Chem. Soc. Ethiop. 2023, 37(4), 931-944. DOI: https://dx.doi.org/10.4314/bcse.v37i4.10
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ژورنال
عنوان ژورنال: Bulletin of The Chemical Society of Ethiopia
سال: 2023
ISSN: ['1011-3924', '1726-801X']
DOI: https://doi.org/10.4314/bcse.v37i4.9